ABSTRACT
Introduction: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an important diagnostic procedure in the lung cancer pathway. False-negative or inadequate sampling can lead to inaccurate staging or delay in diagnosis. This study was conducted to assess the performance of the Cancer EBUS service at a tertiary hospital. Method(s): We conducted a retrospective analysis of patients who underwent EBUS-TBNA for suspected cancer between 1st June 2021 to 31st May 2022. Request forms, CT reports, EBUS reports and pathology reports were reviewed for analysis. Result(s): 205 EBUS-TBNA procedures were performed. All patients had an appropriate staging CT prior to procedure. The mean time to test was 10.5 days (7.4). 77 (38%) had tests within 7 days of request. 293 lymph nodes and 10 mass lesions were sampled. The mean time to pathological results being received was 2.9 days (1.8). Final histology showed 39 (19%) cases of lung adenocarcinomas, 3 (1%) lung non-small cell carcinomas, 25 (12%) lung squamous cell carcinomas, 25 (12%) small cell cancers, 4 (2%) lung NOS, 3 (1%) pulmonary carcinoid, 2 (1%) lymphoma, 12 (6%) other cancers, 12 granulomata and 1 thyroid tissue (6%). 43 (21%) cases showed lymphoid tissue and 28 (14%) were reported as inadequate. No samples were taken in 8 cases (4%). Adequate tissue for predictive marker testing was available in 93% (66) of cases of non-small cell lung cancer (NSCLC). Complications were encountered in 9 cases (4%). Only 3 cases (1.5%) required any form of intervention. [Figure presented] Conclusion(s): Our data provides assurance of safety while also highlighting specific areas for attention regarding performance and time to test that can be addressed and our sensitivity was comparable to national standards. The increased waiting times may be partly related to COVID-19 precautions and will require reauditing at a later date. Disclosure: No significant relationships.Copyright © 2023 Elsevier B.V.
ABSTRACT
Very little research has been conducted on brain tumor epidemiology in Pakistan and a few studies that do exist provide regional data only. Conducting population based epidemiological studies in low-and-middle income countries (LMICs) like Pakistan can be particularly challenging due to limited resources, poor clinical and research infrastructure, unreliable or incomplete hospital records and a lack of standardization across the health care system. Population-wide studies and registries play an important role in cancer epidemiology and can help identify the current magnitude of cancer burden and its likely future evolution, allowing for better planning of prevention, diagnosis, management, and rehabilitation. This paper describes our experience in designing and conducting Pakistan Brain Tumor Epidemiology Study (PBTES), a first-ever nationwide study carried out to assess the distribution of brain tumors in Pakistan. In addition to the aforementioned obstacles, we were also faced with the global health crisis caused by the COVID-19 pandemic and had to promptly adjust our study accordingly. Other investigators conducting epidemiological studies in LMICs with similarly challenging and constricting settings could benefit from our experiences.
ABSTRACT
The COVID-19 epidemic is considered the most important health disaster of the century and the largest humanitarian crisis since World War II. In December 2019, a new respiratory disease/disorder was discovered in Wuhan, Hubei province, China and World Health Organization named it COVID-19 (coronavirus 2019). It has been diagnosed with a new class of corona virus, called SARS-CoV-2 (a serious respiratory disease). According to the history of human civilization it is affected by the incidence of disease outbreaks caused by the number of viruses. Covid-19 is rapidly spreading across the globe, due to which mankind faces major health, economic, environmental and social challenges. The outbreak of coronavirus is seriously affecting the global economy. Almost all nations have problems limiting the spread of the disease by screening and treating patients, setting up suspects by keeping in touch, blocking large gatherings, maintaining full or partial closure etc. This paper describes the impact of COVID-19 on society and the global environment, and the ways in which the disease is likely to be controlled have been discussed.
ABSTRACT
Purpose The study aims to analyze the role of coronavirus testing capacity to possibly reduce the case fatality ratio (CFR) in a large cross-section of countries. The study controlled health-care expenditures, logistics performance index (LPI), carbon damages, and corporate social responsibility (CSR) to understand the nature of causation between the CFR and stated factors. Design/methodology/approach The study used a cross-sectional regression apparatus for coefficient estimates and variance decomposition analysis (VDA) for forecasting relationships between the variables over time. Findings The results confirmed the W-shaped relationship between CFR and case-to-test ratio (CTR) in the presence of a LPI that exacerbates the CFR cases across countries. The VDA estimates suggest that carbon damages, logistics activities, and CSR are likely to influence CFR over time. Originality/value To the best of the authors' knowledge, the study is believed to be the first study that assesses the W-shaped relationship between the CFR and CTR in the presence of dynamic variables, which helps to formulate long-term sustainable health-care policies worldwide.
ABSTRACT
COVID19 has transformed the worldwide education norms of teaching and learning. The customary face-to-face method is currently being substitute with online webinars such as Webex and its counterparts. A survey has been conducted to investigate the experience of online learning among postgraduate in Malaysia.. The survey is divided into two categories of issues related to online teaching and learning and time spent on activities during the Movement Control Order (MCO). Thematic analysis is employed to analyse the data pattern. Three main themes on online learning experience had emerged, namely IT facilities, learning engagement and personal adjustment. This survey also investigates the type of activities pursued during the Movement Control Order (MCO) and found that all the participants spent their time to complete assignments as well as highly video streaming especially from the youtube channel. Though online teaching and learning received a positive response, most students still prefer the face-to-face method compare to fully adopting the online method of teaching and learning. © 2020, Institute of Advanced Scientific Research, Inc.. All rights reserved.